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Testosterone Replacement

Does testosterone cause prostate cancer?

There is no medical evidence that testosterone replacement causes prostate cancer.  This has been confirmed by numerous studies evaluating the risk.

There is no evidence that testosterone replacement therapy causes cardiac problems or strokes.  Studies have shown that men with hypogonadal (low) testosterone levels are actually at a higher risk of major cardiac events.

Testosterone is the original anabolic androgenic steroid. This just means that it has tissue building as well as male masculinizing characteristics.  The public image of athletic or body building “anabolic steroids” are synthetic compounds that are manipulated to have a much higher muscle building effect.

No, testosterone does not inherently change a person’s personality.

Testosterone replacement can lead to decreased sperm production, increased red blood cell production, nipple sensitivity, decreased testicular size, hair loss and/or acne.  Most of these side effects can be controlled by appropriate dosing or assistive medications.

Testosterone replacement can lead to increased energy, improved sense of well-being, loss of body fat, increased lean muscle tissue, increased sexual arousal and improved mental focus.

Yes, when prescribed appropriately testosterone can lead to many of the same improvements in women (increased libido, loss of body fat, improved sense of well-being).

The use of testosterone supplementation will cause a decrease in your natural testosterone level and sperm production.  This can be controlled but you will have decreased chances of conception while on the medication.

No, there are other ways to administer testosterone to a patient (oral or cream).

Yes, enclomiphene citrate and human chorionic gonadotropin (hCG) or two other examples of medications that can potentially increase your natural testosterone level.

Weight Loss Treatments

GLP-1 agonist (semaglutide & tirzepatide), phentermine, phentermine/topiramate, MIC-B12 are all medications that can lead to weight loss.

Typically patients experience nausea, vomiting or GI distress with these medications when either the starting dose is too high or they continue to eat large, infrequent meals.  Appropriate eating patterns are discussed during the consultation.

While the medications can cause sufficient weight loss without diet or exercise, adding these lifestyle changes will result in a healthier, more sustainable weight loss. The hope is that the medications can eventually be tapered down (or discontinued) and dietary/exercise changes will maintain the body composition improvements.

Absolutely.

Average weight loss over one year on the medications:

Semaglutide – 15% of total bodyweight over one year
Tirzepatide – 15-22% of total bodyweight over one year
Phentermine – 5-10% of total body weight
Phentermine/Topiramate – 10-11% of total body weight

Yes, GLP-1 agonist medications are not recommended for women trying to get pregnant, anyone with medullary thyroid cancer, MENs type II neoplasia, acute pancreatitis or acute gallbladder disease.

Sexual Health Treatments

Oral PDE5 inhibitors like sildenafil & tadalafil (Viagra/Cialis), bremelanotide or PT-141 for increased sexual arousal, or Tri-Mix or Quad-Mix penile injections

The procedure uses a very tiny needle (smaller than a diabetic insulin needle) to inject the medication into the base of the penis.  The very first procedure is performed in the office so the patient can be instructed on how it is performed safely.  Patient self-administers thereafter.

Yes, women can potentially benefit from testosterone, bremelanotide, low-dose sildenafil/tadalafil or vaginal arousal creams.

Hair Loss Treatments

Typically oral 5α reductase inhibitors (dutasteride), minoxidil scalp solution/foam and medicated shampoos and conditioners make up the cornerstone of hair treatments.

Hair loss treatments vary in efficacy depending on numerous factors but patients that start treatment in the early stages of hair loss

Yes

Scalp red light therapy, platelet rich plasma (PRP) injections, microneedling, spironolactone, ketoconazole, and hair transplantation are just a few of the many other treatments investigated for hair loss.

Bioidentical Hormone Replacement Therapy (Women)

Bioidentical hormones are hormones that are structurally identical to the natural hormones that the body produces. These hormones are easily detectable in blood analysis so that hormone therapy can be monitored and adjusted based on the fluctuating lab values. Synthetic hormones are typically not detectable in standard laboratory testing.
Hot flashes, night sweats, brain fog, mood changes, incontinence, low libido, pain with intercourse, vaginal pain/irritation, weight gain, sleep disturbances, urinary tract infections, skin/hair/nail changes, heart palpitations, and/or GI symptoms.
Testosterone replacement in women can be beneficial if noticing decreases in libido, energy, mood changes, muscle loss and/or brain fog.

No, topical bioidentical hormone replacement has NOT been shown to increase the risk of breast cancer. Even the previous studies suggesting a risk with the use of oral, synthetic estrogen products are under debate. Micronized bioidentical progesterone usage has not been shown to cause cancers.

Estrogen – Improvements in perimenopausal/menopausal symptoms; improved bone mineral density; improved skin/hair/nail health; reduction in cardiovascular events and all-cause mortality.

Progesterone – Protection of the endometrium, potential improvements in sleep and mood.

Testosterone – Improvements in libido, energy, mood, mental clarity, lean muscle and body composition.

Estrogen replacement may cause some increased breast tenderness and spotting in some patients. Micronized progesterone replacement has very few side effects but some may experience mood swings or ineffectiveness of treatment. Testosterone replacement, at elevated doses, can cause acne, hair growth, mood changes or enlargement of the clitoris. These side effects are typically only seen at significantly high doses of the medication.

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